重组小鼠表皮膜蛋白1
| 英文名称 | Recombinant mouse EMP-1 protein, GST & His |
| 中文名称 | 重组小鼠表皮膜蛋白1 |
| 别 名 | CL-20; EMP 1; EMP1; EMP1_HUMAN; Epithelial membrane protein 1; Protein B4B; TMP; Tumor-associated membrane protein; Recombinant mouse EMP-1 protein, GST & His |
| 理论分子量 | 32kDa |
| 检测分子量 | 32 kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | ＞0.5 mg/ml |
| 物 种 | Mouse |
| 序 列 | 16-64/160 |
| 纯 度 | >95% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | E.coli |
| 活性 | Not tested |
| 标签 | GST & His |
| 缓 冲 液 | 4 M Urea (pH=9.0) |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion. When EMP-1 is overexpressed, cell proliferation is inhibited, S phase is arrested and G1 phase is prolonged in esophogeal cancer cells. EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer. |
| 产品图片 |
 The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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