FITC标记的5-羟色胺受体6抗体
产品名称： FITC标记的5-羟色胺受体6抗体
英文名称： Anti-5HT6 Receptor/FITC
产品编号： HZ-12058R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-5HT6 Receptor/FITC Conjugated antibody
FITC标记的5-羟色胺受体6抗体
| 英文名称 | Anti-5HT6 Receptor/FITC |
| 中文名称 | FITC标记的5-羟色胺受体6抗体 |
| 别 名 | SR-6; 5 HT 6; 5 HT6; 5 hydroxytryptamine 6 receptor; 5 hydroxytryptamine receptor 6; 5-HT-6; 5-HT6; 5-hydroxytryptamine receptor 6; 5HT 6; 5HT6R_HUMAN; HTR 6; HTR6; Serotonin receptor 6. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 神经生物学 细胞膜受体 G蛋白偶联受体 新陈代谢 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 47kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human 5HT6 Receptor/SR-6 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor. [provided by RefSeq, Aug 2013] Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in several human brain regions, most prominently in the caudate nucleus. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 3362 Human Entrez Gene: 15565 Mouse Entrez Gene: 64354 Rat Omim: 601109 Human SwissProt: P50406 Human SwissProt: Q9R1C8 Mouse SwissProt: P31388 Rat Unigene: 22180 Human Unigene: 291096 Mouse Unigene: 10552 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码属于七跨膜G蛋白偶联受体家族的蛋白质。编码蛋白与Gsα亚基偶联，刺激腺苷酸环化酶激活环腺苷酸依赖性信号通路。这种受体被认为可以调节脑内胆碱能神经元的传递。几种抗抑郁药和抗精神病药物对这种受体有很高的亲和力。[ RefSeq，Aug 2013提供]