Recombinant Human Hepatocyte Growth Factor (Human HGF)
产品名称: Recombinant Human Hepatocyte Growth Factor (Human HGF)
英文名称: Recombinant Human Hepatocyte Growth Factor (Human HGF)
产品编号: 92055ES10
产品价格: 815.00
产品产地: Yeasen
品牌商标: Yeasen
更新时间: 2024-12-10T11:18:52
使用范围: null
规格 | 价格 |
10μg | 815.0 |
50μg | 3285.0 |
100μg | 4925.0 |
500μg | 12805.0 |
1mg | 19715.0 |
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Product Information
Product Description
HGF is a potent, mesenchymally-derived mitogen for mature parenchymal hepatocytes, and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include the induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. HGF, also known as scatter factor and hepatopoietin A, is a pleiotropic protein in the plasminogen subfamily of S1 peptidases. It is a multidomain molecule that includes an N-terminal PAN/APPLE‑like domain, four Kringle domains, and a serine proteinase-like domain that has no detectable protease activity.
Product Properties
Synonyms |
Scatter Factor (SF), Hepatopoietin (HPTA) |
Accession |
P14210 |
Gene ID |
3082 |
Source |
CHO-derived Human HGF protein, Gln32-Ser728 |
Molecular Weight |
88~90 kDa (single chain), 59~61 kDa (alpha chain), 30~34 kDa (beta chain), on SDS-PAGE under reducing conditions. |
Tag |
None |
Purity |
> 95% by SDS-PAGE. |
Biological Activity |
ED50 < 10.0 ng/ml, measured in a cell proliferation assay using 4MBr5 cells, corresponding to a specific activity of > 1.0 × 105 units/mg. |
Endotoxin |
< 0.2 EU per 1μg of the protein by the LAL method. |
Formulation |
Lyophilized after extensive dialysis against PBS. |
Reconstitution |
It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -80℃ for 1 year.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
3 months, -20 °C under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
- Avoid repeated freeze-thaw cycles.
- For your safety and health, please wear lab coats and disposable gloves for operation.
- For research use only.
HB240227