TET2抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
TET2抗体

TET2抗体

商家询价

产品名称： TET2抗体

英文名称： TET2Antibody

产品编号： XY 21207-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 TET2 抗体Applications

Tested Applications: ELISA, IP, WB
Cited applications IF, IHC, WB
Specificity Reaction: Human, Mouse; Other species are not tested.Please decide the specificity by homology
Cited species Human
Positive WB detected in HL-60 cells, A549 cells, HEK-293 cells, human brain tissue
Positive IP detected in Mouse brain tissue
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:2000
 TET2 抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 21207-1-AP;HL-60 cellsHL-60 cells were subjected to SDS PAGE followed by western blot with 21207-1-AP(TET2 antibody) at dilution of 1:500
  • 21207-1-AP;mouse brain tissueIP Result of anti-TET2 (IP:21207-1-AP, 3ug; Detection:21207-1-AP 1:500) with mouse brain tissue lysate 4000ug.
Product Information TET2 抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: TET2 fusion protein ag15583 Full Name: Tet oncogene family member 2
Caculated Molecular
Weight:		 2002aa,224 kDa Observed Molecular 
Weight:		 130kd,133kd,224kd
GenbankNo BC150180 GeneID: 54790
Symbol TET2 Synonyms FLJ20032, KIAA1546, tet oncogene family member 2, TET2
Background

TET2 is an enzyme which converts 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) in DNA and is important for normal myelopoiesis. TET2 mutations are frequently observed in myeloid malignancies, including myeloproliferative neoplasms. TET2 is broadly expressed in a variety of tissues. In healthy tissues, TET2 expression was shown to be elevated in hematopoietic cells with highest expression in granulocytes. Three isoforms of TET2 exists due to the alternative splicing. 220-250 kDa bands represent the full-length isoform; 130-133 kDa bands represent the nuclear isoforms of TET2. This antibody recognizes all three isoforms of TET2. TET2 抗体

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