PAPD5抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
PAPD5抗体

PAPD5抗体

商家询价

产品名称: PAPD5抗体

英文名称: PAPD5Antibody

产品编号: XY 55197-1

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 PAPD5抗体Applications

Tested Applications: ELISA, IP
Specificity Reaction: Human; Other species are not tested.Please decide the specificity by homology
Positive IP detected in Jurkat cells
Recommended dilution IP : 1:200-1:2000
 PAPD5抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 55197-1-AP;Jurkat cellsIP Result of anti-PAPD5 (IP:55197-1-AP, 3ug; Detection:55197-1-AP 1:500) with Jurkat cells lysate 1600ug.
Product Information PAPD5抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: Peptide Full Name: PAP associated domain containing 5
Caculated Molecular
Weight:
64 kDa Observed Molecular 
Weight:
63-80 kDa
GenbankNo NM_001040285 GeneID: 64282
Symbol PAPD5 Synonyms FLJ40270, PAPD5, Terminal uridylyltransferase 3, TRF4 2, TUTase 3
Background

PAPD5, also named as Non-canonical poly(A) RNA polymerase PAPD5, is a 572 amino acid protein, which contains 1 PAP-associated domain and belongs to the DNA polymerase type-B-like family. PAPD5 is predominantly expressed in the cytoplasm. PAPD5 as catalytic subunit of a TRAMP-like complex that has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. PAPD5 plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. PAPD5 also may play a role in sister chromatid cohesion. The calculated molecular weight of PAPD5 is a 63 kDa, but the post-modified protein is about 80 kDa. PAPD5抗体

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