MTOR polyclonal antibody
产品名称： MTOR polyclonal antibody
英文名称： MTOR polyclonal antibody
产品编号： PAB10135
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against partial recombinant FRAP1.
- Immunogen:
- Recombinant protein corresponding to human FRAP1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS, pH 7.3 (1% BSA, 0.08% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- Western blot (0.1 to 1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.
Sarbassov DD, Guertin DA, Ali SM, Sabatini DM.Science. 2005 Feb 18;307(5712):1098-101.
- 2.
- mTOR, translational control and human disease.
Tee AR, Blenis J.Semin Cell Dev Biol. 2005 Feb;16(1):29-37. Epub 2004 Dec 31.
- 3.
- Unique, highly proliferative growth phenotype expressed by embryonic and neointimal smooth muscle cells is driven by constitutive Akt, mTOR, and p70S6K signaling and is actively repressed by PTEN.
Mourani PM, Garl PJ, Wenzlau JM, Carpenter TC, Stenmark KR, Weiser-Evans MC.Circulation. 2004 Mar 16;109(10):1299-306. Epub 2004 Mar 1.
- Entrez GeneID:
- 2475
- Gene Name:
- MTOR
- Gene Alias:
- FRAP,FRAP1,FRAP2,RAFT1,RAPT1
- Gene Description:
- mechanistic target of rapamycin
- Omim ID:
- 601231
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq
- Other Designations:
- FK506 binding protein 12-rapamycin associated protein 1,FK506 binding protein 12-rapamycin associated protein 2,FK506-binding protein 12-rapamycin complex-associated protein 1,FKBP-rapamycin associated protein,FKBP12-rapamycin complex-associated protein 1