F8 purified MaxPab mouse polyclonal antibody (B01P)
产品名称： F8 purified MaxPab mouse polyclonal antibody (B01P)
英文名称： F8 purified MaxPab mouse polyclonal antibody (B01P)
产品编号： H00002157-B01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human F8 protein.
- Immunogen:
- F8 (NP_063916.1, 1 a.a. ~ 216 a.a) full-length human protein.
- Sequence:
- MRIQDPGKVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQDLY
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of F8 expression in transfected 293T cell line (H00002157-T01) by F8 MaxPab polyclonal antibody.
Lane 1: F8 transfected lysate(23.76 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 2157
- GeneBank Accession#:
- NM_019863.2
- Protein Accession#:
- NP_063916.1
- Gene Name:
- F8
- Gene Alias:
- AHF,DXS1253E,F8B,F8C,FVIII,HEMA
- Gene Description:
- coagulation factor VIII, procoagulant component
- Omim ID:
- 306700
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq
- Other Designations:
- OTTHUMP00000061446,OTTHUMP00000196174,coagulation factor VIII,coagulation factor VIIIc,factor VIII F8B,procoagulant component
- Interactome
- Gene Pathway
- Related Disease
- Abortion, Habitual
- Activated Protein C Resistance
- Anemia, Sickle Cell
- Anemia, sickle cell
- Arteriosclerosis
- Atherosclerosis
- Autoimmune Diseases
- Cardiovascular Diseases
- Cerebral Hemorrhage
- Cerebrovascular Disorders
- Chromosome Inversion
- Coronary Disease
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Fetal Growth Retardation
- Genetic Predisposition to Disease
- Hemophilia A