BST2 purified MaxPab mouse polyclonal antibody (B02P)
产品名称： BST2 purified MaxPab mouse polyclonal antibody (B02P)
英文名称： BST2 purified MaxPab mouse polyclonal antibody (B02P)
产品编号： H00000684-B02P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human BST2 protein.
- Immunogen:
- BST2 (NP_004326.1, 1 a.a. ~ 180 a.a) full-length human protein.
- Sequence:
- MASTSYDYCRVPMEDGDKRCKLLLGIGILVLLIIVILGVPLIIFTIKANSEACRDGLRAVMECRNVTHLLQQELTEAQKGFQDVEAQAATCNHTVMALMASLDAEKAQGQKKVEELEGEITTLNHKLQDASAEVERLRRENQVLSVRIADKKYYPSSQDSSSAAAPQLLIVLLGLSALLQ
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Publication Reference
- 1.
- Lack of adaptation to human tetherin in HIV-1 Group O and P.
Yang SJ, Lopez LA, Exline CM, Haworth KG, Cannon PM.Retrovirology. 2011 Sep 28;8:78.
- 2.
- Tethered virions are intermediates in the assembly and release of HIV-1 particles.
Karetnikov A, Suomalainen M.Virology. 2010 Nov 25;407(2):289-95. Epub 2010 Sep 20.
- 3.
- Tetherin Restricts Productive HIV-1 Cell-to-Cell Transmission.
Casartelli N, Sourisseau M, Feldmann J, Guivel-Benhassine F, Mallet A, Marcelin AG, Guatelli J, Schwartz O.PLoS Pathog. 2010 Jun 17;6(6):e1000955.
- 4.
- HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment.
Hauser H, Lopez LA, Yang SJ, Oldenburg JE, Exline CM, Guatelli JC, Cannon PM.Retrovirology. 2010 Jun 7;7:51.
- 5.
- Ebola glycoprotein counteracts BST-2/tetherin restriction in a sequence independent manner that does not require tetherin surface removal.
Lopez LA, Yang SJ, Hauser H, Exline CM, Haworth KG, Oldenburg J, Cannon PM.J Virol. 2010 May 5. [Epub ahead of print]
- 6.
- Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration.
Gupta RK, Mlcochova P, Pelchen-Matthews A, Petit SJ, Mattiuzzo G, Pillay D, Takeuchi Y, Marsh M, Towers GJ.Proc Natl Acad Sci U S A. 2009 Oct 28. [Epub ahead of print]
- 7.
- HIV-1 Accessory Protein Vpu Internalizes Cell-surface BST-2/Tetherin through Transmembrane Interactions Leading to Lysosomes.
Iwabu Y, Fujita H, Kinomoto M, Kaneko K, Ishizaka Y, Tanaka Y, Sata T, Tokunaga K.J Biol Chem. 2009 Dec 11;284(50):35060-72. Epub 2009 Oct 16.
- Applications
- Western Blot (Tissue lysate)
- BST2 MaxPab polyclonal antibody. Western Blot analysis of BST2 expression in human spleen.
- Protocol Download
- Western Blot (Cell lysate)
- BST2 MaxPab polyclonal antibody. Western Blot analysis of BST2 expression in Jurkat.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of BST2 expression in transfected 293T cell line (H00000684-T02) by BST2 MaxPab polyclonal antibody.
Lane 1: BST2 transfected lysate(19.8 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of purified MaxPab antibody to BST2 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml]
- Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of purified MaxPab antibody to BST2 on HeLa cell. [antibody concentration 10 ug/ml]
- Protocol Download
- Entrez GeneID:
- 684
- GeneBank Accession#:
- NM_004335
- Protein Accession#:
- NP_004326.1
- Gene Name:
- BST2
- Gene Alias:
- CD317
- Gene Description:
- bone marrow stromal cell antigen 2
- Omim ID:
- 600534
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq
- Other Designations:
- tetherin
- Related Disease