ATP6AP1 (Human) Recombinant Protein (P01)
产品名称： ATP6AP1 (Human) Recombinant Protein (P01)
英文名称： ATP6AP1 (Human) Recombinant Protein (P01)
产品编号： H00000537-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Human ATP6AP1 full-length ORF ( NP_001174.2, 1 a.a. - 470 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MMAAMATARVRMGPRCAQALWRMPWLPVFLSLAAAAAAAAAEQQVPLVLWSSDRDLWAPAADTHEGHITSDLQLSTYLDPALELGPRNVLLFLQDKLSIEDFTAYGGVFGNKQDSAFSNLENALDLAPSSLVLPAVDWYAVSTLTTYLQEKLGASPLHVDLATLRELKLNASLPALLLIRLPYTASSGLMAPREVLTGNDEVIGQVLSTLKSEDVPYTAALTAVRPSRVARDVAVVAGGLGRQLLQKQPVSPVIHPPVSYNDTAPRILFWAQNFSVAYKDQWEDLTPLTFGVQELNLTGSFWNDSFARLSLTYERLFGTTVTFKFILANRLYPVSARHWFTMERLEVHSNGSVAYFNASQVTGPSIYSFHCEYVSSLSKKGSLLVARTQPSPWQMMLQDFQIQAFNVMGEQFSYASDCASFFSPGIWMGLLTSLFMLFIFTYGLHMILSLKTMDRFDDHKGPTISLTQIV
- Theoretical MW (kDa):
- 78.4
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Publication Reference
- 1.
- Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR.J Biol Chem. 2011 Oct 10.
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 537
- GeneBank Accession#:
- NM_001183.4
- Protein Accession#:
- NP_001174.2
- Gene Name:
- ATP6AP1
- Gene Alias:
- 16A,ATP6IP1,ATP6S1,Ac45,CF2,MGC129781,VATPS1,XAP-3,XAP3
- Gene Description:
- ATPase, H+ transporting, lysosomal accessory protein 1
- Omim ID:
- 300197
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene is approximately 45 kD and may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. [provided by RefSeq
- Other Designations:
- ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1,ATPase, H+ transporting, lysosomal interacting protein 1,H-ATPase subunit,OTTHUMP00000032115,V-ATPase S1 accessory protein
- Related Disease