TBP monoclonal antibody-抗体-抗体-生物在线
亚诺法生技股份有限公司（Abnova)
TBP monoclonal antibody

TBP monoclonal antibody

商家询价

产品名称： TBP monoclonal antibody

英文名称： TBP monoclonal antibody

产品编号： MAB0121

产品价格： null

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围：

亚诺法生技股份有限公司（Abnova)
  • 联系人 :
  • 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
  • 邮编 : 11493
  • 所在区域 : 台湾
  • 电话 : +886-920**1152 点击查看
  • 传真 : 点击查看
  • 邮箱 : sales@abnova.com.tw
进入展台

  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinantt TBP.
  • Immunogen:
  • Recombinant protein corresponding to N-terminus of human TBP.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Storage Buffer:
  • In PBS (0.02% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • ChIP
  • ChIP
  • ChIP results obtained with the TBP monoclonal antibody (Cat # MAB0121). ChIP assays were performed using U-2 OS cells.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 6908
  • Gene Name:
  • TBP
  • Gene Alias:
  • GTF2D,GTF2D1,MGC117320,MGC126054,MGC126055,SCA17,TFIID
  • Gene Description:
  • TATA box binding protein
  • Gene Summary:
  • Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminal. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. Mutations that expand the number of CAG repeats encoding this polyglutamine tract, and thus increase the length of the polyglutamine string, are associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000017703

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