NPM1 polyclonal antibody
产品名称: NPM1 polyclonal antibody
英文名称: NPM1 polyclonal antibody
产品编号: PAB17900
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of NPM1.
- Immunogen:
- A synthetic peptide corresponding to the residues surrounding amino acid the N-terminus of human NPM1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (50% glycerol, 1% BSA, 0.02% thimerosal)
- Storage Instruction:
- Store at -20°C. For long term storage store at -80°.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
Immunohistochemistry (10-20 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Western Blot
- Immunohistochemistry
- Entrez GeneID:
- 4869
- Protein Accession#:
- P06748
- Gene Name:
- NPM1
- Gene Alias:
- B23,MGC104254,NPM
- Gene Description:
- nucleophosmin (nucleolar phosphoprotein B23, numatrin)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF (MIM 600160). NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia (AML; MIM 601626) (Garzon et al., 2008 [PubMed 18308931]).[supplied by OMIM
- Other Designations:
- nucleolar phosphoprotein B23,nucleophosmin 1,nucleophosmin/nucleoplasmin family, member 1,numatrin
- Related Disease
- Acute Disease
- Blast Crisis
- Cell Transformation, Neoplastic
- Chromosome Aberrations
- Disease Progression
- Genetic Predisposition to Disease
- Inversion, Chromosome
- Leukemia, chronic myeloid
- Leukemia, Myelocytic, Acute
- Leukemia, Myeloid
- Leukemia, Myeloid, Acute
- Leukemia, Myelomonocytic, Chronic
- Leukemia, Nonlymphocytic, Acute
- Leukemia, Promyelocytic, Acute
- Myelodysplastic Syndromes
- Neoplasm, Residual
- Recurrence
- Translocation, Genetic