ATF2 (phospho S472) polyclonal antibody
产品名称： ATF2 (phospho S472) polyclonal antibody
英文名称： ATF2 (phospho S472) polyclonal antibody
产品编号： PAB8127
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of ATF2.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S472 of human ATF2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Peptide affinity purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Biliverdin reductase, a novel regulator for induction of activating transcription factor-2 and heme oxygenase-1.
Kravets A, Hu Z, Miralem T, Torno MD, Maines MD.J Biol Chem. 2004 May 7;279(19):19916-23. Epub 2004 Feb 25.
- 2.
- Activation and interaction of ATF2 with the coactivator ASC-2 are responsive for granulocytic differentiation by retinoic acid.
Hong S, Choi HM, Park MJ, Kim YH, Choi YH, Kim HH, Choi YH, Cheong J.J Biol Chem. 2004 Apr 23;279(17):16996-7003. Epub 2004 Jan 20.
- 3.
- Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation.
Averous J, Bruhat A, Jousse C, Carraro V, Thiel G, Fafournoux P.J Biol Chem. 2004 Feb 13;279(7):5288-97. Epub 2003 Dec 1.
- Entrez GeneID:
- 1386
- Protein Accession#:
- NP_001871;A1L3Z2
- Gene Name:
- ATF2
- Gene Alias:
- CRE-BP1,CREB2,HB16,MGC111558,TREB7
- Gene Description:
- activating transcription factor 2
- Omim ID:
- 123811
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. [provided by RefSeq
- Other Designations:
- OTTHUMP00000163262,activating transcription factor 2 splice variant ATF2-var2,cAMP responsive element binding protein 2, formerly
- Gene Pathway