MSTN (N-term) Peptide
产品名称： MSTN (N-term) Peptide
英文名称： MSTN (N-term) Peptide
产品编号： P0860
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MSTN.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to amino acids 17-46 at N-terminus of human MSTN.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The myostatin propeptide and the follistatin-related gene are inhibitory binding proteins of myostatin in normal serum.
Hill JJ, Davies MV, Pearson AA, Wang JH, Hewick RM, Wolfman NM, Qiu Y.J Biol Chem. 2002 Oct 25;277(43):40735-41. Epub 2002 Aug 22.
- 2.
- Bone mineral content and density in the humerus of adult myostatin-deficient mice.
Hamrick MW, McPherron AC, Lovejoy CO.Calcif Tissue Int. 2002 Jul;71(1):63-8. Epub 2002 Jun 13.
- 3.
- Insulin-like growth factor-1 and myostatin mRNA expression in muscle: comparison between 62-77 and 21-31 yr old men.
Welle S, Bhatt K, Shah B, Thornton C.Exp Gerontol. 2002 Jun;37(6):833-9.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of MSTN polyclonal antibody (Cat # PAB3887) in mouse liver tissue lysate. MSTN (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with MSTN polyclonal antibody (Cat # PAB3887) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 2660
- Protein Accession#:
- O14793
- Gene Name:
- MSTN
- Gene Alias:
- GDF8
- Gene Description:
- myostatin
- Omim ID:
- 601788
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. [provided by RefSeq
- Other Designations:
- growth differentiation factor 8