HOXA13 polyclonal antibody
产品名称： HOXA13 polyclonal antibody
英文名称： HOXA13 polyclonal antibody
产品编号： PAB14641
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of HOXA13.
- Immunogen:
- A synthetic peptide corresponding to amino acids 291-306 of human HOXA13.
- Host:
- Rabbit
- Reactivity:
- Bovine, Chicken, Chimpanzee, Dog, Human, Mouse, Rat
- Specificity:
- The amino acid sequence used as immunogen is 100% homologous in human, dog, chimp and bovine, and 93% homologous in mouse, rat and chicken.
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.2% gelatin, 0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:100-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The chromosome translocation t(7;11)(p15;p15) in acute myeloid leukemia results in fusion of the NUP98 gene with a HOXA cluster gene, HOXA13, but not HOXA9.
Taketani T, Taki T, Ono R, Kobayashi Y, Ida K, Hayashi Y.Genes Chromosomes Cancer. 2002 Aug;34(4):437-43.
- 2.
- A novel stable polyalanine [poly(A)] expansion in the HOXA13 gene associated with hand-foot-genital syndrome: proper function of poly(A)-harbouring transcription factors depends on a critical repeat length?
Utsch B, Becker K, Brock D, Lentze MJ, Bidlingmaier F, Ludwig M.Hum Genet. 2002 May;110(5):488-94. Epub 2002 Apr 4.
- Application Image
- ELISA
- Entrez GeneID:
- 3209
- Protein Accession#:
- NP_000513;NM_000522
- Gene Name:
- HOXA13
- Gene Alias:
- HOX1,HOX1J
- Gene Description:
- homeobox A13
- Gene Ontology:
- Hyperlink
- Gene Summary:
- In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. [provided by RefSeq
- Other Designations:
- homeo box 1J,homeo box A13,homeobox protein HOXA13,transcription factor HOXA13
- Related Disease