HIRA monoclonal antibody, clone WC119.2H11
产品名称： HIRA monoclonal antibody, clone WC119.2H11
英文名称： HIRA monoclonal antibody, clone WC119.2H11
产品编号： MAB8967
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant HIRA.
- Amount:
- 100 uL
- Immunogen:
- Recombinant protein corresponding to amino acids 421-729 of human HIRA.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody reacts with human HIRA.
- Form:
- Liquid
- Purification:
- Purified ascites
- Concentration:
- 1 ug/uL
- Isotype:
- IgG1
- Storage Buffer:
- In PBS, pH 7.4 (0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Entrez GeneID:
- 7290
- Gene Name:
- HIRA
- Gene Alias:
- DGCR1,TUP1,TUPLE1
- Gene Description:
- HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- Omim ID:
- 600237
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq
- Other Designations:
- DiGeorge critical region gene 1,HIR histone cell cycle regulation defective homolog A
- Related Disease