DPABH-01332 detects endogenous levels of GRLF1 only when phosphorylated at Tyrosine 1087.Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5-GAGAAAAGAAACTGGAGAAACTC-3. May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as a tumor suppressor.Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. *   http://www.creative-diagnostics.com/Anti-ARHGAP35-PAb-199469-489.htm