MAP3K1 polyclonal antibody
产品名称: MAP3K1 polyclonal antibody
英文名称: MAP3K1 polyclonal antibody
产品编号: PAB2272
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MAP3K1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MAP3K1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension.
Xia Y, Wu Z, Su B, Murray B, Karin M.Genes Dev. 1998 Nov 1;12(21):3369-81.
- 2.
- Mapping of the MEK kinase gene (Mekk) to mouse chromosome 13 and human chromosome 5.
Vinik BS, Kay ES, Fiedorek FT Jr.Mamm Genome. 1995 Nov;6(11):782-3.
- Entrez GeneID:
- 4214
- Protein Accession#:
- Q13233
- Gene Name:
- MAP3K1
- Gene Alias:
- MAPKKK1,MEKK,MEKK1
- Gene Description:
- mitogen-activated protein kinase kinase kinase 1
- Omim ID:
- 600982
- Gene Ontology:
- Hyperlink
- Gene Summary:
- MAP3K, or MEK kinase, is a serine/threonine kinase that occupies a pivotal role in a network of phosphorylating enzymes integrating cellular responses to a number of mitogenic and metabolic stimuli, including insulin (MIM 176730) and many growth factors.[supplied by OMIM
- Other Designations:
- MAP/ERK kinase kinase 1,MAPK/ERK kinase kinase 1,MEK kinase 1,OTTHUMP00000065818
- Related Disease
- Adenocarcinoma
- Arthritis, Rheumatoid
- Breast cancer
- Breast Neoplasms
- Cardiovascular Diseases
- Colitis, Ulcerative
- Crohn Disease
- Crohn's disease
- Diabetes Mellitus, Type 2
- Disease Susceptibility
- Edema
- Endometrial Neoplasms
- Genetic Predisposition to Disease
- Lymphatic Metastasis
- Neoplasm Invasiveness
- Neoplasms, Hormone-Dependent
- Ovarian cancer
- Ovarian Neoplasms
- Pancreatic Neoplasms