GDF10 (N-term) Peptide
产品名称： GDF10 (N-term) Peptide
英文名称： GDF10 (N-term) Peptide
产品编号： P0852
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of GDF10.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human GDF10.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The family of bone morphogenetic proteins.
Ducy P, Karsenty G.Kidney Int. 2000 Jun;57(6):2207-14.
- 2.
- cDNA cloning and genomic structure of human bone morphogenetic protein-3B (BMP-3b).
Hino J, Takao M, Takeshita N, Konno Y, Nishizawa T, Matsuo H, Kangawa K.Biochem Biophys Res Commun. 1996 Jun 14;223(2):304-10.
- 3.
- Growth/differentiation factor-10: a new member of the transforming growth factor-beta superfamily related to bone morphogenetic protein-3.
Cunningham NS, Jenkins NA, Gilbert DJ, Copeland NG, Reddi AH, Lee SJ.Growth Factors. 1995;12(2):99-109.
- Applications
- Western Blot (Cell lysate)
- The GDF10 polyclonal antibody (Cat # PAB3881) is used in Western blot to detect GDF10 in A-375 cell lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with GDF10 polyclonal antibody (Cat # PAB3881) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
- Entrez GeneID:
- 2662
- Protein Accession#:
- NP_004953
- Gene Name:
- GDF10
- Gene Alias:
- BMP-3b,BMP3B
- Gene Description:
- growth differentiation factor 10
- Omim ID:
- 601361
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019534,bone morphogenetic protein 3B